How Does Nerivio Work?

Nerivio® uses Remote Electrical Neuromodulation (REN) to prevent and treat migraines. This innovative technology is delivered through a wearable device that stimulates the nerves to block migraine signals. Clinical trials have shown that Nerivio provides consistent relief from migraine pain and associated symptoms. It is safe, well-tolerated, and does not carry the risk of medication overuse.

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  1. A discreet wearable device, non-disruptive to your daily routine.

  2. Drug-free, Non-invasive

  3. Can be used instead of or with medications

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Novel Mechanism of Action

Nerivio stimulates Aδ and C fibers in the upper arm. Stimulation of these pain fibers sends messages to the pain regulation centers in the brainstem. This activates the body’s Conditioned Pain Modulation (CPM) system, activating the descending pain inhibitory pathways. Descending inhibitory signals travel to the trigeminal cervical complex where serotonin and norepinephrine are released. Nerivio’s activation of the body’s endogenous analgesic system has a global impact on pain.

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